Anti-Somatostatin Receptor 1/SSTR1 antibody (ab100881)
Key features and details
- Rabbit polyclonal to Somatostatin Receptor 1/SSTR1
- Suitable for: ICC/IF
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-Somatostatin Receptor 1/SSTR1 antibody
See all Somatostatin Receptor 1/SSTR1 primary antibodies -
Description
Rabbit polyclonal to Somatostatin Receptor 1/SSTR1 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Horse, Cow, Dog, Human, Pig -
Immunogen
Synthetic peptide corresponding to Mouse Somatostatin Receptor 1/SSTR1 aa 374-391 (C terminal).
Sequence:ESGGVFRNGTCASRISTL
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab100881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use at an assay dependent concentration.
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Notes |
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ICC/IF
Use at an assay dependent concentration. |
Target
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Function
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. -
Tissue specificity
Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 6751 Human
- Entrez Gene: 25033 Rat
- Omim: 182451 Human
- SwissProt: P30872 Human
- SwissProt: P28646 Rat
- Unigene: 248160 Human
- Unigene: 42915 Rat
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Alternative names
- G-protein coupled receptor antibody
- Somatostatin R1 antibody
- Somatostatin receptor 1 antibody
see all
Images
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ab100881 at 1/5000 showing dual labeling of anti-sst1 (green) and somatostatin (red). Anti-Sst1 shows sst1 in neuronal terminals co-localized with somatostatin
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ab100881 showing anti-Sst1 depicts sst1 as a presynaptic receptor in the superficial layers of the spinal cord dorsal horn.
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Immunocytochemistry/ Immunofluorescence showing Somatostatin Receptor 1/SSTR1 staining in rat brain using ab100881.
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab100881 has been referenced in 1 publication.
- Cai L et al. HOTAIR Accelerates Dyskinesia in a MPTP-Lesioned Mouse Model of PD via SSTR1 Methylation-Mediated ERK1/2 Axis. Mol Ther Nucleic Acids 22:140-152 (2020). PubMed: 32927363