Anti-CXCL16 antibody (ab101404)

Overview

• Product nameAnti-CXCL16 antibodySee all CXCL16 primary antibodies ...
• Description
  Rabbit polyclonal to CXCL16
• Tested applicationsWB, IHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant protein fragment containing a sequence corresponding to a region within amino acids 52-193 of Human CXCL16 (AAH17588).

• Positive controlA549, HepG2 whole cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Immunology
  • Innate Immunity
  • Chemokines
  • Alpha Chemokines (CXC)

Applications

Target

• FunctionActs as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
• Tissue specificityExpressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
• Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
• Post-translational
  modificationsGlycosylated.
• Cellular localizationCell membrane. Secreted. Also exists as a soluble form.

Target information above from: UniProt accession Q9H2A7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 58191 Human
  • Omim: 605398 Human
  • SwissProt: Q9H2A7 Human
  • Unigene: 513885 Human
  • Unigene: 730800 Human

• Alternative names
  C-X-C motif chemokine 16 antibodyChemokine (C X C motif) ligand 16 antibodyCXC chemokine ligand 16 antibody

  Cxcl16 antibodyCXCLG16 antibodyCXL16_HUMAN antibodyScavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibodySCYB16 antibodySmall inducible cytokine B16 precursor antibodySmall-inducible cytokine B16 antibodySR-PSOX antibodySRPSOX antibodyTransmembrane chemokine CXCL16 antibodyUNQ2759/PRO6714 antibody

  see all

Anti-CXCL16 antibody images

• 

  Western blot - CXCL16 antibody (ab101404)
  Anti-CXCL16 antibody (ab101404) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
  
  Predicted band size : 28 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CXCL16 antibody (ab101404)
  Immunohistochemical analysis of paraffin-embedded H661 xenograft, using ab101404 at 1/100 dilution.