Anti-MMS22L (C6ORF167) antibody (ab101888)

Overview

• Product nameAnti-MMS22L (C6ORF167) antibody
• Description
  Rabbit polyclonal to MMS22L (C6ORF167)
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Horse, Cow
• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 450 - 550 of Human MMS22L (C6ORF167) .

  Read Abcam's proprietary immunogen policy

• Positive controlThis antibody gave a positive signal in Human liver tissue lysate.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7.40
  Preservative: 0.02% Sodium azide
  Constituent: PBS
  Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • DNA Synthesis
  • Other

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • DNA Damage & Repair
  • Homologous Recomb.

Applications

Target

• FunctionComponent of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.
• Sequence similaritiesBelongs to the MMS22 family. MMS22L subfamily.
• Cellular localizationNucleus. Localizes to DNA damage sites, accumulates at stressed replication forks.

Target information above from: UniProt accession Q6ZRQ5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 532916 Cow
  • Entrez Gene: 253714 Human
  • SwissProt: Q6ZRQ5 Human
  • Unigene: 444292 Human

• Alternative names
  C6orf167 antibodyC6orf167 chromosome 6 open reading frame 167 antibodychromosome 6 open reading frame 167 antibody

  dJ39B17.2 antibodyDKFZp686C20164 antibodyDKFZp781C2113 antibodyFLJ46180 antibodyhomologous to yeast Mms22 antibodyKIAA1900 antibodyMethyl methanesulfonate-sensitivity protein 22-like antibodyMMS22 like, DNA repair protein antibodyMms22-like protein antibodyMMS22_HUMAN antibodyMMS22L antibodyOTTHUMP00000221009 antibodyProtein MMS22-like antibodyUncharacterized protein C6orf167 antibody

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Anti-MMS22L (C6ORF167) antibody images

• 

  Western blot - 19. MMS22L (C6ORF167) antibody (ab101888)
  Anti-MMS22L (C6ORF167) antibody (ab101888) at 1 µg/ml + Liver (Human) Tissue Lysate - adult normal tissue (ab29889) at 10 µg
  
  Secondary
  Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed (ab97080) at 1/5000 dilution
  developed using the ECL technique
  
  Performed under reducing conditions.
  
  Predicted band size : 142 kDa
  Observed band size : 155 kDa (why is the actual band size different from the predicted?)
  
  
  Exposure time : 3 minutes