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RabMAbs (3606-1)

Anti-CD42a antibody [EPR5295] (ab108304)

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Overview

  • Product nameAnti-CD42a antibody [EPR5295]See all CD42a primary antibodies ...
  • Description
    Rabbit monoclonal [EPR5295] to CD42a
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human

    Does not react with

    Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to residues in the extracellular domain of human CD42a

  • Positive controlHuman platelet lysate
  • General notesProduced under U.S. Patent No. 5,675,063

Properties

  • FormLiquid
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • PurityTissue culture supernatant
  • Clonality Monoclonal
  • Clone numberEPR5295
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab108304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/1000 - 1/10000. Predicted molecular weight: 19 kDa.
  • Application notesIs unsuitable for ,ICC,IHC-P or IP.

    • Target

    • FunctionThe GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
    • Involvement in diseaseDefects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
    • Sequence similaritiesContains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • Cellular localizationMembrane.

      • Target information above from: UniProt accession P14770 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          CD42a antibodyGlycoprotein 9 antibodyGlycoprotein IX antibody
          Glycoprotein IX (platelet) antibodyGlycoprotein IX precursor antibodyGP IX antibodyGP-IX antibodyGP9 antibodyGPIX antibodyGPIX_HUMAN antibodyPlatelet glycoprotein IX antibody
        see all

      Anti-CD42a antibody [EPR5295] images

      • Western blot - CD42a antibody [EPR5295] (ab108304)
        Western blot - CD42a antibody [EPR5295] (ab108304)
        Anti-CD42a antibody [EPR5295] (ab108304) at 1/1000 dilution + Human platelet lysate at 10 µg

        Performed under reducing conditions.

        Predicted band size : 19 kDa

      References for Anti-CD42a antibody [EPR5295] (ab108304)

      ab108304 has not yet been referenced specifically in any publications.

      Publishing research using ab108304 ? Please let us know so that we can cite the reference in this datasheet

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"