Parainfluenza Virus IgG Human ELISA Kit (ab108758)
Overview
- Product nameParainfluenza Virus IgG Human ELISA Kit
- Detection methodColorimetric
- Tests1 x 96 well plate
- Sample typeSerum, Plasma
- Assay typeIndirect
- Assay durationMultiple steps standard assay
- Species reactivityReacts with: Human
- Product overview
Ab108758, Parainfluenza Virus IgG ELISA Kit is intended for the qualitative determination of IgG class antibodies against Parainfluenza Virus (Types 1, 2, 3) IgG in Human serum or plasma (citrate).
Parainfluenza viruses are important viral pathogens causing upper and lower respiratory infections in adults and children. The viruses belong to the family of Paramyxoviridae. They are enveloped single-stranded RNA viruses with spherical or pleomorphic shape. Parainfluenza viruses are relatively large viruses of about 150-300 nm in diameter. On the basis of antigenic differences they are divided into four subtypes, of which type 4 is divided into two subtypes. Parainfluenza virus 1 and 3 belong to the paramyxovirus genus. Parainfluenza virus 2, 4a and 4b belong to the rubella virus genus along with mumps. The virus is ubiquitous; infections occur as epidemics as well as sporadically. Parainfluenza viruses are sensitive to detergents and heat but can remain viable on surfaces for up to 10 hours. Transmission occurs via droplets, aerosols and fomites (viruses survive on surfaces). Parainfluenza virus infections are primarily childhood diseases, the highest age-specific attack rates for croup occur in children below the age of 3 years. Type 3 infections occur earliest and most frequently, so that ~50% of children are infected during the first year of life and almost all by 6 years, as determined by seroepidemiological studies. Antibodies against types 1 and 2 are acquired less rapidly but 80% of children have antibodies by 10 years of age. Type 4 viruses induce few clinical illnesses but infections are common, 70 - 80% of children have antibodies by 10 years of age. In all age groups, the incubation period appears to be five to six days. Croup or laryngotracheobronchitis is the commonest clinical manifestation of infection. Parainfluenza viruses are found uncommonly associated with other respiratory tract infections in children such as tracheobronchitis, bronchiolitis, and bronchopneumonia. Occasionally, a mild non-specific illness is seen after parainfluenza virus infection. In adults, the virus is usually limited to causing inflammation in the upper parts of the respiratory tract.
- Tested applicationsIndirect ELISA more details
- PlatformMicroplate
Properties
- Storage instructionsStore at +4°C. Please refer to protocols.
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Components Identifier 1 x 96 tests IgG Sample Diluent white cap 1 x 100ml Parainfluenza Virus anti-IgG Conjugate black cap 1 x 20ml Parainfluenza Virus Coated Wells (IgG) 1 unit Parainfluenza Virus IgG Cut-off Control green cap 1 x 3ml Parainfluenza Virus IgG Negative Control blue cap 1 x 2ml Parainfluenza Virus IgG Positive Control red cap 1 x 2ml Stop Solution Red cap 1 x 15ml TMB Substrate Solution yellow cap 1 x 15ml Washing Solution (20X) white cap 1 x 50ml - Research Areas
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Alternative names
- Parainfluenza VirusParainfluenza Virus IgG
Applications
Our Abpromise guarantee covers the use of ab108758 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Indirect ELISA | I-ELISA |
Protocols
References for Parainfluenza Virus IgG Human ELISA Kit (ab108758)
ab108758 has not yet been referenced specifically in any publications.
