Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281] (ab109746)

Overview

• Product nameAnti-Myelin oligodendrocyte glycoprotein antibody [EP4281]See all Myelin oligodendrocyte glycoprotein primary antibodies ...
• Description
  Rabbit monoclonal [EP4281] to Myelin oligodendrocyte glycoprotein
• Tested applicationsWB, IHC-P, ICC more details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  Synthetic peptide corresponding to residues in the extracellular domain of Human Myelin oligodendrocyte glycoprotein

• Positive controlMouse brain, Rat brain and Human brain lysates; Human astrocytoma tissue and Human brain tissue
• General notesProduced under U.S. Patent No. 5,675,063.

Properties

• FormLiquid
• Storage instructionsStore at -20°C. Stable for 12 months at -20°C
• Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• PurityTissue culture supernatant
• Clonality Monoclonal
• Clone numberEP4281
• IsotypeIgG
• Research Areas
  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Axon marker

  • Neuroscience
  • Cell Type Marker
  • Glia marker
  • Oligodendrocyte marker

  • Neuroscience
  • Neurology process
  • Neuroregeneration
  • Neuroregeneration

  • Neuroscience
  • Neurology process
  • Neurogenesis

Applications

Target

• FunctionMediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
• Tissue specificityFound exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
• Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
  Contains 1 Ig-like V-type (immunoglobulin-like) domain.
• Cellular localizationCell membrane.

Target information above from: UniProt accession Q16653 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 4340 Human
  • Entrez Gene: 17441 Mouse
  • Entrez Gene: 24558 Rat
  • Omim: 159465 Human
  • SwissProt: Q16653 Human
  • SwissProt: Q61885 Mouse
  • SwissProt: Q63345 Rat
  • Unigene: 141308 Human

  • Unigene: 210857 Mouse
  • Unigene: 9687 Rat

  see all

• Alternative names
  MGC26137 antibodyMOG alpha 6 antibodyMOG antibody

  MOG Ig AluB antibodyMOG_HUMAN antibodyMOGIG2 antibodyMyelin oligodendrocyte glycoprotein antibodyMyelin-oligodendrocyte glycoprotein antibody

  see all

Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281] images

• 

  Western blot - Myelin oligodendrocyte glycoprotein antibody [EP4281] (ab109746)
  All lanes : Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281] (ab109746) at 1/1000 dilution
  
  Lane 1 : Mouse brain lysate
  Lane 2 : Rat brain lysate
  Lane 3 : Human brain lysate
  
  Lysates/proteins at 10 µg per lane.
  
  
  Predicted band size : 28 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Myelin oligodendrocyte glycoprotein antibody [EP4281] (ab109746)
  ab109746, at 1/1000 dilution, staining Myelin oligodendrocyte glycoprotein in paraffin-embedded Human astrocytoma tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Myelin oligodendrocyte glycoprotein antibody [EP4281] (ab109746)
  ab109746, at 1/1000 dilution, staining Myelin oligodendrocyte glycoprotein in paraffin-embedded Human brain tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Breast carcinoma tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Normal breast tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing positive staining in Glioblastoma tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Colonic adenocarcinoma tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Normal tonsil tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Normal colon tissue.
  
  
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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myelin oligodendrocyte glycoprotein antibody [EP4281](ab109746)
  ab109746 showing negative staining in Benign prostatic hyperplasia tissue.