Anti-ARHGEF11 antibody (ab110059)
- Product nameAnti-ARHGEF11 antibodySee all ARHGEF11 primary antibodies ...
- DescriptionRabbit polyclonal to ARHGEF11
- SpecificityThis antibody detects endogenous levels of total ARHGEF11 protein.
- Tested applicationsWB more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide derived from the N terminal region of Human ARHGEF11.
- Positive controlA549 and COLO cell extracts.
- Storage instructionsStore at -20°C. Stable for 12 months at -20°C
- Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
Note: PBS without Mg2+ and Ca2+
- Concentration information loading...
- PurityImmunogen affinity purified
- Purification notesab110059 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab110059 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: 1/500 - 1/1000. Predicted molecular weight: 168 kDa.|
- FunctionMay play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
- Tissue specificityUbiquitously expressed.
- Sequence similaritiesContains 1 DH (DBL-homology) domain.
Contains 1 PDZ (DHR) domain.
Contains 1 PH domain.
Contains 1 RGSL (RGS-like) domain.
- DomainThe poly-Pro region is essential for plasma membrane localization upon stimulation.
- Cellular localizationCytoplasm. Membrane. Translocated to the membrane upon stimulation.
- ARHGB_HUMAN antibodyARHGEF 11 antibodyARHGEF11 antibody
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Anti-ARHGEF11 antibody images
All lanes : Anti-ARHGEF11 antibody (ab110059) at 1/500 dilution
Lane 1 : A549 cell extract
Lane 2 : COLO cell extract
Lane 3 : COLO cell extract with immunizing peptide
Lysates/proteins at 30 µg per lane.
Predicted band size : 168 kDa
References for Anti-ARHGEF11 antibody (ab110059)
ab110059 has not yet been referenced specifically in any publications.