LAT protein (ab113124)
Constituents: 0.32% Tris HCl, 0.02% DTT
Our Abpromise guarantee covers the use of ab113124 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution.|
|MS||MS: Use at an assay dependent concentration.|
- 36 kDa phospho tyrosine adapter protein36 kDa phospho-tyrosine adapter protein36 kDa phospho-tyrosine adaptor protein
- latLAT 1LAT_HUMANLAT1Linker for activation of T cellsLinker for activation of T cells family member 1linker for activation of T cells, transmembrane adaptorLinker for activation of T-cells family member 1p36 38p36-38pp36
modificationsPhosphorylated on tyrosines by ZAP-70 upon TCR activation, or by SYK upon other immunoreceptor activation; which leads to the recruitment of multiple signaling molecules. Is one of the most prominently tyrosine-phosphorylated proteins detected following TCR engagement. May be dephosphorylated by PTPRJ.
Palmitoylation of Cys-26 and Cys-29 is required for raft targeting and efficient phosphorylation.
LAT protein images
15% SDS-PAGE analysis of ab113124 (3 µg).
Molecular weight on SDS-PAGE will appear higher.
References for LAT protein (ab113124)
ab113124 has not yet been referenced specifically in any publications.