Anti-APC2 antibody (ab113370)
Overview
- Product nameAnti-APC2 antibodySee all APC2 primary antibodies ...
- DescriptionRabbit polyclonal to APC2
- Tested applicationsWB, ELISA, IHC-P, ICC more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse - Immunogen
Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human APC2 (NP_005874.1).
- Positive controlHuman Brain Cortex and Small Intestine tissues; HeLa cell lysate.
Properties
- FormLiquid
- Storage instructionsStore at 4°C, stable for one year. Should not be exposed to prolonged high temperatures. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... - PurityProtein A purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab113370 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa. |
| ELISA | ELISA: Use at an assay dependent dilution. |
| IHC-P | IHC-P: Use a concentration of 5 µg/ml. |
| ICC | ICC: Use at an assay dependent dilution. |
Target
- RelevanceAPC2 might function in the Wnt signaling pathway through it's ability to promote the rapid degradation of beta-catenin. It also functions as a tumour suppressor.
- Cellular localizationCell Membrane, Cytoplasmic and Golgi Apparatus
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Database links
- Entrez Gene: 10297 Human
- SwissProt: O95996 Human
- SwissProt: Q9Z1K7 Mouse
- Unigene: 446376 Human
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Alternative names
- Adenomatous polyposis coli protein 2 antibodyAdenomatous polyposis coli protein-like antibodyAPCL antibody
Anti-APC2 antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry. -
Western blot - Anti-APC2 antibody (ab113370)Lane 1 : Anti-APC2 antibody (ab113370) at 1 µg/ml
Lane 2 : Anti-APC2 antibody (ab113370) at 2 µg/ml
Lane 1 : HeLa cell lysate
Lane 2 : HeLa cell lysate
Predicted band size : 244 kDa
References for Anti-APC2 antibody (ab113370)
This product has been referenced in:
- Hebert AM et al. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev 26:2709-23 (2012). WB ; Human . Read more (PubMed: 23249734) »
