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Overview

  • Product nameCytochrome P450 3A5 protein
  • Protein descriptionRecombinant full length Human Cytochrome P450 3A5 (amino acids 1-502) with N terminal proprietary tag; Predicted MWt 80.96 kDa (UniProt P20815).
  • Uniprot accessionP20815
  • Molecular weight80.960kDa inclusive of tags
  • Protein length502 amino acids
  • Expression hostWheat germ

    • Properties

  • E.C. Number1.14.14.1
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Sequence notesMDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPG PTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLP VLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISL AEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNL RREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQ DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSL FPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQN SKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYE LATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVV NETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYA LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRN CIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG LLQPEKPIVLKVDSRDGTLSGE
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab114670 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    WB WB: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        Aryl hydrocarbon hydroxylaseCP35CP3A5_HUMAN
        CYP3A5CYPIIIA5Cytochrome P450Cytochrome P450 3A5Cytochrome P450 family 3 subfamily A polypeptide 5Cytochrome P450 HLp2Cytochrome P450 subfamily IIIA (niphedipine oxidase) polypeptide 5Cytochrome P450-PCN3DKFZp686L16231Flavoprotein linked monooxygenaseFLJ31317HLp2Microsomal monooxygenaseNiphedipine oxidaseP450PCN3PCN3Xenobiotic monooxygenase
      see all
  • FunctionCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.

    • Target information above from: UniProt accession P20815 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Cytochrome P450 3A5 protein images

    • SDS-PAGE - Cytochrome P450 3A5 protein (ab114670)
      SDS-PAGE - Cytochrome P450 3A5 protein (ab114670)
      SDS-PAGE analysis of ab114670 on a 12.5% gel stained with Coomassie Blue.

    References for Cytochrome P450 3A5 protein (ab114670)

    ab114670 has not yet been referenced specifically in any publications.

    Publishing research using ab114670 ? Please let us know so that we can cite the reference in this datasheet

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