Anti-CD38 antibody [GR7A4] (CF405M) (ab117772)

Overview

• Product nameAnti-CD38 antibody [GR7A4] (CF405M)See all CD38 primary antibodies ...
• Description
  Mouse monoclonal [GR7A4] to CD38 (CF405M)
• ConjugationCF405M
• Conjugation notesCF405M (Abs/Em Max: 408/450nm).  Direct replacement for Pacific Blue dye®, BD Horizon™ V450
• Tested applicationsFlow Cyt more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Cells of Human Acute Lymphoblastic B leukaemia (B-ALL)

• Positive controlHuman bone marrow cells.

Properties

• FormLiquid
• Storage instructionsStore at +4°C in the dark.
• Storage bufferpH: 7.20
  Preservative: 0.09% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Monoclonal
• Clone numberGR7A4
• IsotypeIgG1
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Hypoxia

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • T Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Monocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • NK Cell Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Hematopoietic Stem Cells
  • Human Lineage Negative

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • B Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Surface Molecules

  • Cancer
  • Cancer Metabolism
  • Response to hypoxia

  • Immunology
  • Adaptive Immunity
  • Regulatory T Cells

  • Immunology
  • Adaptive Immunity
  • B Cells
  • CD

Applications

Target

• FunctionSynthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
• Tissue specificityExpressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
• Sequence similaritiesBelongs to the ADP-ribosyl cyclase family.
• Developmental stagePreferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
• Cellular localizationMembrane.

Target information above from: UniProt accession P28907 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 952 Human
  • Omim: 107270 Human
  • SwissProt: P28907 Human
  • Unigene: 479214 Human

• Alternative names
  Acute lymphoblastic leukemia cells antigen CD38 antibodyADP ribosyl cyclase 1 antibodyADP ribosyl cyclase antibody

  ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibodyADP-ribosyl cyclase 1 antibodycADPr hydrolase 1 antibodyCD 38 antibodyCD38 antibodyCD38 antigen (p45) antibodyCD38 antigen antibodyCD38 molecule antibodyCd38-rs1 antibodyCD38_HUMAN antibodyCD38H antibodyCyclic ADP ribose hydrolase antibodyCyclic ADP ribose hydrolase 1 antibodyCyclic ADP-ribose hydrolase 1 antibodyEC 3.2.2.5 antibodyEcto nicotinamide adenine dinucleotide glycohydrolase antibodyI-19 antibodyI19 (mouse) antibodyLymphocyte differentiation antigen CD38 antibodyNAD(+) nucleosidase antibodyNIM-R5 antigen antibodyNIMR5 antigen (mouse) antibodyOTTHUMP00000158633 antibodyOTTHUMP00000217743 antibodyp45 antibodyT10 antibody

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Anti-CD38 antibody [GR7A4] (CF405M) images

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  Flow Cytometry - Anti-CD38 antibody [GR7A4] (CF405M) (ab117772)
  ab117772 at 5µl/10⁶ cells staining CD38 in Human bone marrow cells by Flow Cytometry.