Anti-VMAT2 antibody [10C11] (ab117988)

Overview

• Product nameAnti-VMAT2 antibody [10C11]See all VMAT2 primary antibodies ...
• Description
  Mouse monoclonal [10C11] to VMAT2
• Tested applicationsIHC-P, WB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant Human VMAT2 expressed in 293T cells

• Positive controlHEK293T cell lysate transfected with pCMV6-ENTRY VMAT2 cDNA; Human breast adenocarcinoma, kidney carcinaoma, ovary and endometrium tissues.
• General notesDilute in PBS (pH7.3) before use.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: 48% PBS, 1% BSA, 50% Glycerol
• Concentration information loading...
• PurityProtein G purified
• Purification notesab117988 was purified from mouse ascites fluids by affinity chromatography.
• Clonality Monoclonal
• Clone number10C11
• IsotypeIgG1
• Research Areas
  • Neuroscience
  • Neurotransmitter
  • Biogenic Amines
  • Noradrenaline

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Parkinson's disease
  • Other

  • Neuroscience
  • Neurotransmitter
  • Transporters
  • Dopamine

  • Neuroscience
  • Neurotransmitter
  • Transporters
  • Other Transporters

  • Neuroscience
  • Neurotransmitter
  • Biogenic Amines
  • Serotonin / 5HT

  • Neuroscience
  • Neurotransmitter
  • Biogenic Amines
  • Dopamine

  • Neuroscience
  • Neurotransmitter
  • Biogenic Amines
  • Histamine

  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • Other

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Other

Applications

Target

• FunctionInvolved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
• Sequence similaritiesBelongs to the major facilitator superfamily. Vesicular transporter family.
• Cellular localizationCytoplasmic vesicle membrane.

Target information above from: UniProt accession Q05940 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 6571 Human
  • Omim: 193001 Human
  • SwissProt: Q05940 Human
  • Unigene: 596992 Human

• Alternative names
  1110037L13Rik antibody9330105E13 antibodyMGC120477 antibody

  MGC120478 antibodyMGC26538 antibodyMGC90556 antibodyMNAT antibodyMonoamine neurotransmitter transporter antibodyMonoamine transporter antibodyOTTHUMP00000020576 antibodySLC18A2 antibodySolute carrier family 18 (vesicular monoamine) member 2 antibodySolute carrier family 18 member 2 antibodySVAT antibodySVMT antibodySynaptic vesicle amine transporter brain antibodySynaptic vesicle monoamine transporter brain antibodySynaptic vesicular amine transporter antibodyVAT 2 antibodyVAT2 antibodyVesicle monoamine transporter type 2 antibodyVesicle monoamine/H+ antiporter antibodyVesicular amine transporter 2 antibodyVesicular monoamine transporter 2 antibodyVMAT 2 antibodyVMAT2 antibodyVMAT2_HUMAN antibody

  see all

Anti-VMAT2 antibody [10C11] images

• 

  Western blot - Anti-VMAT2 antibody [10C11] (ab117988)
  All lanes : Anti-VMAT2 antibody [10C11] (ab117988) at 1/500 dilution
  
  Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
  Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY VMAT2 cDNA
  
  Lysates/proteins at 5 µg per lane.
  
  
  Predicted band size : 56 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VMAT2 antibody [10C11] (ab117988)
  ab117988, at 1/50 dilution, staining VMAT2 in paraffin-embedded Human breast adenocarcinoma tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VMAT2 antibody [10C11] (ab117988)
  ab117988, at 1/50 dilution, staining VMAT2 in paraffin-embedded Human kidney carcinoma tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VMAT2 antibody [10C11] (ab117988)
  ab117988, at 1/50 dilution, staining VMAT2 in paraffin-embedded Human ovary tissue by Immunohistochemistry.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VMAT2 antibody [10C11] (ab117988)
  ab117988, at 1/50 dilution, staining VMAT2 in paraffin-embedded Human endometrium tissue by Immunohistochemistry.