2-Chloroadenosine (CADO), Adenosine agonist (ab120037)
Key features and details
- Adenosine agonist
- CAS Number: 146-77-0
- Soluble in DMSO to 25 mM and in water to 25mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Chloroadenosine (CADO), Adenosine agonist -
Description
Adenosine agonist -
Alternative names
- CADO
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Biological description
Adenosine receptor agonist. Metabolically stable analogue of adenosine. Anticonvulsant effects and neuroprotective in vivo.
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CAS Number
146-77-0 -
Chemical structure
Properties
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Chemical name
6-Amino-2-chloropurine riboside -
Molecular weight
301.69 -
Molecular formula
C10H12ClN5O4 -
PubChem identifier
44320877 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in water to 25mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Nc3nc(Cl)nc2c3ncn2C1O[C@H](CO)[C@@H](O)[C@H]1O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab120037 has been referenced in 2 publications.
- Elmasri M et al. Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A. Commun Biol 5:174 (2022). PubMed: 35228668
- Di Angelantonio S et al. Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human (alpha)3(beta)4 nicotinic receptor. J Physiol 589:2755-66 (2011). PubMed: 21486776