Angiotensin II (human), Vasoconstrictor peptide (ab120183)
Key features and details
- Vasoconstrictor peptide
- CAS Number: 4474-91-3
- Soluble in water to 1mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Angiotensin II (human), Vasoconstrictor peptide -
Description
Vasoconstrictor peptide -
Biological description
Endogenous peptide involved in body water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and sexual behaviours, and the regulation of pituitary gland hormones.
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CAS Number
4474-91-3 -
Chemical structure
Properties
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Molecular weight
1046.18 -
Molecular formula
C50H71N13O12 -
Sequence
DRVYIHPF -
PubChem identifier
172198 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 1mg/ml -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (19)
ab120183 has been referenced in 19 publications.
- Tanrıverdi LH et al. Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II-induced hypertension. Fundam Clin Pharmacol 37:60-74 (2023). PubMed: 36117326
- Guo J et al. Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms. Biomolecules 13:N/A (2023). PubMed: 37371479
- Shen A et al. Based on network pharmacology, gastrodin attenuates hypertension-induced vascular smooth muscle cell proliferation and PI3K/AKT pathway activation. Sci Rep 13:12140 (2023). PubMed: 37495624
- Shangguan W et al. Cfa-circ002203 was upregulated in rapidly paced atria of dogs and involved in the mechanisms of atrial fibrosis. Front Cardiovasc Med 10:1110707 (2023). PubMed: 37593150
- Guo J et al. Metformin protects against abdominal aortic aneurysm by Atg7-induced autophagy. Adv Clin Exp Med 31:59-69 (2022). PubMed: 34714980