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Overview

  • Product nameALDOB protein (His tag)See all ALDOB proteins and peptides ...
  • Protein descriptionRecombinant full length protein (amino acids 1-364) of Human ALDOB with an N terminal His tag; 388 amino acids with the tag, predicted mwt: 42 kDa (NP_000026).
  • Uniprot accessionP05062
  • Molecular weight42kDa inclusive of tags
  • Protein length36 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab123165 is purified using conventional chromatography techniques.
  • Mass spectrometryMALDI-TOF
  • E.C. Number4.1.2.13
  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
  • Concentration information loading...
  • Sequence notesMGSSHHHHHHSSGLVPRGSHMGSHMAHRFPALTQEQKKEL SEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENR RQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRN ILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCA QYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYAS ICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKA LNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTA LHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPW KLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAMANC QAAKGQYVHTGSSGAASTQSLFTACYTY
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab123165 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    MS MS: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab137628,ab138760 and ab153828.

    • Protein info

    • Alternative names
        ALDBALDO BALDO2
        ALDOBALDOB_HUMANAldolase 2Aldolase BAldolase B fructose bisphosphateAldolase2AldolaseBEC 4.1.2.13Fructose bisphosphate aldolase BFructose-bisphosphate aldolase BLiver type aldolaseLiver-type aldolaseMS1077
      see all
  • PathwayCarbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
  • Involvement in diseaseDefects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.
  • Sequence similaritiesBelongs to the class I fructose-bisphosphate aldolase family.

    • Target information above from: UniProt accession P05062 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    ALDOB protein (His tag) images

    • SDS-PAGE - ALDOB protein (His tag) (ab123165)
      SDS-PAGE - ALDOB protein (His tag) (ab123165)
      15% SDS-PAGE showing ab123165 (3 µg) at approximately 42 kDa.

    References for ALDOB protein (His tag) (ab123165)

    ab123165 has not yet been referenced specifically in any publications.

    Publishing research using ab123165 ? Please let us know so that we can cite the reference in this datasheet

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