Anti-RPS7 antibody (ab126115)

Overview

• Product nameAnti-RPS7 antibodySee all RPS7 primary antibodies ...
• Description
  Rabbit polyclonal to RPS7
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Cat, Xenopus laevis, Zebrafish
• Immunogen

  Recombinant fragment, corresponding to a region within amino acids 1-173 of Human RPS7 (P62081).

• Positive controlA549 whole cell lysate.

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferpH: 7.00
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 78% PBS, 20% Glycerol, 1% BSA
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Ribosome

Applications

Target

• FunctionRequired for rRNA maturation.
• Involvement in diseaseDefects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
• Sequence similaritiesBelongs to the ribosomal protein S7e family.

Target information above from: UniProt accession P62081 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 505507 Cow
  • Entrez Gene: 6201 Human
  • Entrez Gene: 20115 Mouse
  • Entrez Gene: 29258 Rat
  • Entrez Gene: 397774 Xenopus laevis
  • Entrez Gene: 414368 Xenopus laevis
  • Entrez Gene: 393725 Zebrafish
  • Omim: 603658 Human

  • SwissProt: A6H769 Cow
  • SwissProt: P62081 Human
  • SwissProt: P62082 Mouse
  • SwissProt: P62083 Rat
  • SwissProt: P02362 Xenopus laevis
  • SwissProt: P62084 Zebrafish
  • Unigene: 7187 Cow
  • Unigene: 534346 Human
  • Unigene: 546287 Human
  • Unigene: 646582 Human
  • Unigene: 279839 Mouse
  • Unigene: 371579 Mouse
  • Unigene: 107039 Rat
  • Unigene: 224475 Rat
  • Unigene: 47699 Xenopus laevis
  • Unigene: 855 Xenopus laevis
  • Unigene: 28230 Zebrafish

  see all

• Alternative names
  40S ribosomal protein S7 antibodyDBA8 antibodyRibosomal protein S7 antibody

  RPS 7 antibodyrps7 antibodyRS7_HUMAN antibodyS7 antibody

  see all

Anti-RPS7 antibody images

• 

  Western blot - Anti-RPS7 antibody (ab126115)
  Anti-RPS7 antibody (ab126115) at 1/500 dilution + A549 cell lysate at 30 µg
  
  Predicted band size : 22 kDa