You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-Axl antibody [1B3A2]See all Axl primary antibodies ...
  • Description
    Mouse monoclonal [1B3A2] to Axl
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 466-530 of Human Axl expressed in E.coli.

  • Positive controlTruncated Axl recombinant protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab130177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/2000. Predicted molecular weight: 98 kDa.
ELISA ELISA: 1/10000.

Target

  • FunctionMay function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.
  • Tissue specificityHighly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P30530 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Adhesion related kinase antibodyAI323647 antibodyArk antibody
        Axl antibodyAXL oncogene antibodyAXL receptor tyrosine kinase antibodyAXL transforming gene antibodyAXL transforming sequence/gene antibodyEC 2.7.10.1 antibodyJTK11 antibodyOncogene AXL antibodyTyro7 antibodyTyrosine protein kinase receptor UFO antibodyTyrosine-protein kinase receptor UFO antibodyUFO antibodyUFO_HUMAN antibody
      see all

    Anti-Axl antibody [1B3A2] images

    • Western blot - Anti-Axl antibody [1B3A2] (ab130177)
      Western blot - Anti-Axl antibody [1B3A2] (ab130177)
      Anti-Axl antibody [1B3A2] (ab130177) at 1/500 dilution + Truncated Axl recombinant protein

      Predicted band size : 98 kDa

    References for Anti-Axl antibody [1B3A2] (ab130177)

    ab130177 has not yet been referenced specifically in any publications.

    Publishing research using ab130177 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit a Question for ab130177

    There are currently no Questions for ab130177.
    Please use the link above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"