Anti-Carcino Embryonic Antigen CEA antibody [3G12] (ab130211)

Overview

• Product nameAnti-Carcino Embryonic Antigen CEA antibody [3G12]See all Carcino Embryonic Antigen CEA primary antibodies ...
• Description
  Mouse monoclonal [3G12] to Carcino Embryonic Antigen CEA
• Tested applicationsWB, ICC/IF more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Purified recombinant fragment of Human Carcino Embryonic Antigen CEA expressed in E. Coli.

• Positive controlCarcino Embryonic Antigen CEA-hIgGFc transfected HEK293 cell lysate; PANC1 cells.

Properties

• FormLiquid
• Storage instructionsStore at 4°C. Aliquot and store at -20°C long-term.
• Storage bufferPreservative: 0.03% Sodium azide
  Constituent: 99% Ascites
• Concentration information loading...
• PurityAscites
• Clonality Monoclonal
• Clone number3G12
• IsotypeIgG1
• Research Areas
  • Stem Cells
  • Mesenchymal Stem Cells
  • Surface Molecules

  • Cancer
  • Tumor immunology
  • Tumor-associated antigens

  • Cancer
  • Tumor biomarkers
  • Tumor antigens

  • Tags & Cell Markers
  • Cell Type Markers
  • Tumor Associated

Applications

Target

• FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
• Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
• Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
  Contains 7 Ig-like (immunoglobulin-like) domains.
• Post-translational
  modificationsComplex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
• Cellular localizationCell membrane.

Target information above from: UniProt accession P06731 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 1048 Human
  • Omim: 114890 Human
  • SwissProt: P06731 Human
  • Unigene: 709196 Human

• Alternative names
  Carcinoembryonic antigen antibodyCarcinoembryonic antigen-related cell adhesion molecule 5 antibodyCD66e antibody

  CEA antibodyCeacam5 antibodyCEAM5_HUMAN antibodyDKFZp781M2392 antibodyMeconium antigen 100 antibodyOTTHUMP00000199032 antibodyOTTHUMP00000199033 antibodyOTTHUMP00000199034 antibody

  see all

Anti-Carcino Embryonic Antigen CEA antibody [3G12] images

• 

  Western blot - Anti-CEACAM7 antibody [3G12] (ab130211)
  All lanes : Anti-Carcino Embryonic Antigen CEA antibody [3G12] (ab130211) at 1/500 dilution
  
  Lane 1 : HEK293 cell lysate.
  Lane 2 : Carcino Embryonic Antigen CEA-hIgGFc transfected HEK293 cell lysate.
  
  
  Predicted band size : 77 kDa
  
• 

  Immunocytochemistry/ Immunofluorescence - Anti-CEACAM7 antibody [3G12] (ab130211)
  ab130211 at 1/200 dilution staining Carcino Embryonic Antigen CEA in PANC1 cells by Immunofluorescence (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.