Anti-LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

Overview

• Product nameAnti-LAMP1 antibody [LY1C6] - Lysosome MarkerSee all LAMP1 primary antibodies ...
• Description
  Mouse monoclonal [LY1C6] to LAMP1 - Lysosome Marker
• Tested applicationsWB, IP, ICC, ICC/IF more details
• Species reactivity
  Reacts with: Mouse, Rat, Hamster
  
• Immunogen

  Rat liver lysosomal membrane preparations

• Positive controlHighly purified rat lysosomal membrane preparations.
• General notesFor maximum product recovery centrifuge the product vial before removing cap.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: 50% Glycerol, PBS, pH 7.4
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• Clone numberLY1C6
• IsotypeIgG1
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Autophagy and mitophagy

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Monocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • B Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • T Lymphocytic Lineage

  • Cancer
  • Signal transduction
  • Autophagy

  • Signal Transduction
  • Protein Trafficking
  • Organelle Proteins

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Lysosome

  • Neuroscience
  • Neurology process
  • Neurogenesis

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Growth Cone

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Soma marker

Applications

Target

• FunctionPresents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
• Sequence similaritiesBelongs to the LAMP family.
• Post-translational
  modificationsO- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.
• Cellular localizationCell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Target information above from: UniProt accession P11279 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 16783 Mouse
  • Entrez Gene: 25328 Rat
  • SwissProt: P11438 Mouse
  • SwissProt: P14562 Rat
  • Unigene: 16716 Mouse
  • Unigene: 475822 Mouse
  • Unigene: 40177 Rat

• Alternative names
  CD107 antigen like family member A antibodyCD107 antigen-like family member A antibodyCD107a antibody

  CD107a antigen antibodyLAMP 1 antibodyLAMP-1 antibodyLAMP1 antibodyLAMP1_HUMAN antibodyLAMPA antibodyLGP120 antibodylgpA antibodyLysosomal membrane glycoprotein 120KD antibodyLysosomal Associated Membrane Protein 1 antibodyLysosome associated membrane glycoprotein 1 antibodyLysosome-associated membrane glycoprotein 1 antibodyLysosome-associated membrane protein 1 antibodyOTTHUMP00000040663 antibody

  see all

Anti-LAMP1 antibody [LY1C6] - Lysosome Marker images

• 

  Immunocytochemistry/ Immunofluorescence - LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

  ab13523 at 1/100 dilution staining LAMP1 in LAMP1 transfected HeLa cells by Immunocytochemistry/ immunofluorescence. A Alexa Fluor® 568 conjugated goat anti mouse was used at 1/50 dilution as secondary.

• 

  Western blot - Anti-LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

  Image from Banno A et al, J Biol Chem. 2012 Apr 20;287(17):13799-812. Epub 2012 Feb 18, Fig 4. DOI 10.1074/jbc.M112.341214 April 20, 2012 The Journal of Biological Chemistry, 287, 13799-13812.