Anti-Glucosidase 2 subunit beta antibody (ab136254)

Overview

• Product nameAnti-Glucosidase 2 subunit beta antibodySee all Glucosidase 2 subunit beta primary antibodies ...
• Description
  Rabbit polyclonal to Glucosidase 2 subunit beta
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse
• Immunogen

  Synthetic peptide derived from an internal region of Human Glucosidase 2 subunit beta.

• Positive control293 cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at -20ºC.
• Storage bufferpH: 7.40
  Preservative: 0.02% Sodium azide
  Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
  Note: PBS is without Mg²⁺ and Ca²⁺.
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab136254 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • PKC

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • ER

Applications

Target

• FunctionRegulatory subunit of glucosidase II.
• PathwayGlycan metabolism; N-glycan metabolism.
• Involvement in diseaseDefects in PRKCSH are a cause of polycystic liver disease (PCLD) [MIM:174050]. PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease (ADPKD) [MIM:173900], which in a considerable but uncertain proportion of cases is associated with hepatic cysts.
• Sequence similaritiesContains 2 EF-hand domains.
  Contains 1 PRKCSH domain.
• Cellular localizationEndoplasmic reticulum.

Target information above from: UniProt accession P14314 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5589 Human
  • Entrez Gene: 5589 Human
  • Entrez Gene: 5589 Human
  • Entrez Gene: 19089 Mouse
  • Omim: 177060 Human
  • SwissProt: P14314 Human
  • SwissProt: P14314 Human
  • SwissProt: P14314 Human

  • SwissProt: O08795 Mouse
  • Unigene: 610830 Human
  • Unigene: 214593 Mouse

  see all

• Alternative names
  80K-H protein antibodyAGE-binding receptor 2 antibodyAGE-R2 antibody

  G19P1 antibodyGLU2B_HUMAN antibodyGlucosidase 2 subunit beta antibodyGlucosidase II beta subunit antibodyGlucosidase II subunit beta antibodyHepatocystin antibodyPCLD antibodyPKCSH antibodyPLD1 antibodyPRKCSH antibodyProtein kinase C substrate 60.1 kDa protein heavy chain antibodyProtein kinase C substrate 80 Kda protein antibodyProtein kinase C substrate 80K-H antibodyProtein kinase C substrate, 80 Kda protein antibody

  see all

Anti-Glucosidase 2 subunit beta antibody images

• 

  Western blot - Anti-Glucosidase 2 subunit beta antibody (ab136254)
  Anti-Glucosidase 2 subunit beta antibody (ab136254) at 1/500 dilution + 293 cell lysate at 30 µg
  
  Predicted band size : 59 kDa