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Anti-CD35 antibody [Ber-MAC DRC] (ab16720)

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Overview

  • Product nameAnti-CD35 antibody [Ber-MAC DRC]See all CD35 primary antibodies ...
  • Description
    Mouse monoclonal [Ber-MAC DRC] to CD35
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Suspended human tonsillar cells.

  • Positive controlTonsil

Properties

Applications

Our Abpromise guarantee covers the use of ab16720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notes
    IHC-P: 1/10 - 1/20.
    We suggested an incubation period of 30-60 minutes at room temperature. Proteolytic treatment is required prior to immunostaining of formalin-fixed paraffin-embedded tissue sections.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionMediates cellular binding of particles and immune complexes that have activated complement.
    • Tissue specificityPresent on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.
    • Sequence similaritiesBelongs to the receptors of complement activation (RCA) family.
      Contains 30 Sushi (CCP/SCR) domains.
    • Cellular localizationMembrane.

      • Target information above from: UniProt accession P17927 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          C3 binding protein antibodyC3b/C4b receptor antibodyC3BR antibody
          C4BR antibodyCD 35 antibodyCD35 antibodyCD35 antigen antibodycomplement component (3b/4b) receptor 1 (Knops blood group) antibodycomplement component (3b/4b) receptor 1 including Knops blood group system antibodyComplement component receptor 1 antibodyComplement receptor 1 antibodyComplement receptor type 1 antibodyCR 1 antibodyCR1 antibodyCR1_HUMAN antibodyKN antibodyKnops blood group antigen antibody
        see all

      References for Anti-CD35 antibody [Ber-MAC DRC] (ab16720)

      ab16720 has not yet been referenced specifically in any publications.

      Publishing research using ab16720 ? Please let us know so that we can cite the reference in this datasheet

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      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-CD35 antibody [Ber-MAC DRC]

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      Abreviews
      Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      Sample Human Tissue sections (kidney)
      Specification kidney
      Fixative formalin
      Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate buffer pH 6.0
      Permeabilization No
      Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 20°C
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      Submitted Jan 09 2008

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"