Anti-Prostaglandin E Receptor EP1/PTGER1 antibody (ab183073)
Key features and details
- Rabbit polyclonal to Prostaglandin E Receptor EP1/PTGER1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Prostaglandin E Receptor EP1/PTGER1 antibody
See all Prostaglandin E Receptor EP1/PTGER1 primary antibodies -
Description
Rabbit polyclonal to Prostaglandin E Receptor EP1/PTGER1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human Prostaglandin E Receptor EP1/PTGER1 aa 350 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Genbank: NP_000946
Database link: P34995 -
Positive control
- 293T cell lysate, Human lymphoma tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
(PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab183073 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/450 - 1/5000. Predicted molecular weight: 42 kDa.
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Notes |
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WB
1/450 - 1/5000. Predicted molecular weight: 42 kDa. |
Target
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Relevance
PTGER1 is a subtype 1 receptor for prostaglandin E2 (PGE2). This receptor is coupled to the phosphatidylinositol-calcium second messenger system by G(q) proteins. PTGER1 may be an important modulator of renal function and is implicated in the smooth muscle contractile response to PGE2 in various tissues. -
Cellular localization
Cell Membrane; multi-pass membrane protein. -
Database links
- Entrez Gene: 5731 Human
- Entrez Gene: 19216 Mouse
- Entrez Gene: 25637 Rat
- Omim: 176802 Human
- SwissProt: P34995 Human
- SwissProt: P35375 Mouse
- SwissProt: P70597 Rat
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Alternative names
- EP1 antibody
- PGE receptor EP1 subtype antibody
- PGE2 receptor EP1 subtype antibody
see all
Images
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All lanes : Anti-Prostaglandin E Receptor EP1/PTGER1 antibody (ab183073) at 1/450 dilution
Lane 1 : Human lymphoma tissue lysate
Lane 2 : 293T cell lysate
Lysates/proteins at 40 µg per lane.
Secondary
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 42 kDa
Exposure time: 1 minute10%SDS-PAGE
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab183073 has been referenced in 2 publications.
- Kowalczyk-Zieba I et al. Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling. Animals (Basel) 11:N/A (2021). PubMed: 34573602
- Lu JW et al. Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition. FASEB J 33:8148-8160 (2019). PubMed: 30917001