You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-RRM2 antibodySee all RRM2 primary antibodies ...
  • Description
    Chicken polyclonal to RRM2
  • Specificityab26170 recognises Ribonucleoside-diphosphate reductase M2 subunit.
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQ, corresponding to amino acids 1-92 of Human RRM2

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein L purified
  • Clonality Polyclonal
  • IsotypeIgY
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab26170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/2000. Predicted molecular weight: 45 kDa.

Target

  • FunctionProvides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • PathwayGenetic information processing; DNA replication.
  • Sequence similaritiesBelongs to the ribonucleoside diphosphate reductase small chain family.
  • Post-translational
    modifications    Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession P31350 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        R2 antibodyRibonucleoside diphosphate reductase M2 subunit antibodyRibonucleoside-diphosphate reductase subunit M2 antibody
        Ribonucleotide reductase M2 polypeptide antibodyRibonucleotide reductase M2 subunit antibodyRibonucleotide reductase small chain antibodyRibonucleotide reductase small subunit antibodyRIR2_HUMAN antibodyRR 2 antibodyRR2 antibodyRR2M antibodyRRM 2 antibodyRRM2 antibody
      see all

    Anti-RRM2 antibody images

    • Western blot - RRM2 antibody (ab26170)
      Western blot - RRM2 antibody (ab26170)
      Anti-RRM2 antibody (ab26170) at 1/2000 dilution + E coli-derived RRM2 fusion protein

      Secondary
      Goat anti-IgY-HRP diluted 1/1000

      Predicted band size : 45 kDa

    References for Anti-RRM2 antibody (ab26170)

    ab26170 has not yet been referenced specifically in any publications.

    Publishing research using ab26170 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab26170

    Filter by Application

    Filter by Species

    Filter by Ratings

    Displaying 1 - 1 of 1 results for Abreviews

    10
    Votes: Highest First

    Western blot abreview for Anti-RRM2 antibody

     Inconclusive
    Abreviews
    Application Western blot
    Sample Human Cell lysate - whole cell (fibroblast)
    Loading amount 10000 cells
    Specification fibroblast
    Gel Running Conditions Reduced Denaturing (4-20% acrylamide SDS-PAGE)
    Blocking step Milk as blocking agent for 8 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
    Read More
    Username

    Verified customer

    Submitted Feb 24 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"