Anti-PBP antibody (ab2634)

Overview

• Product nameAnti-PBP antibodySee all PBP primary antibodies ...
• Description
  Goat polyclonal to PBP
• Tested applicationsIHC-P, WB more details
• Species reactivity
  Reacts with: Rat, Human
  Predicted to work with: Mouse, Cow, Dog
• Immunogen

  Synthetic peptide: DYVPKLYEQLSGK, corresponding to C terminal amino acids 174-186 of Human PBP.

  Run BLAST with Run BLAST with
• Positive controlA549, HepG2, HEK293 and human liver lysate.
• General notesGenBank Accession Number – NP_002558.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• PurityIgG fraction
• Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • Other

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Kinases/Phosphatases
  • Other

  • Neuroscience
  • Neurotransmitter
  • Neuropeptides
  • More Neuropeptides

  • Neuroscience
  • Neurotransmitter
  • Acetylcholine

  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Other

  • Cell Biology
  • Cell Cycle
  • Cell Division
  • Spindle

Applications

Target

• FunctionBinds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase.
  HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor.
• Sequence similaritiesBelongs to the phosphatidylethanolamine-binding protein family.
• Cellular localizationCytoplasm.

Target information above from: UniProt accession P30086 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 431786 Cow
  • Entrez Gene: 477501 Dog
  • Entrez Gene: 5037 Human
  • Entrez Gene: 23980 Mouse
  • Entrez Gene: 29542 Rat
  • Omim: 604591 Human
  • SwissProt: P13696 Cow
  • SwissProt: Q3YIX4 Dog

  • SwissProt: P30086 Human
  • SwissProt: P70296 Mouse
  • SwissProt: P31044 Rat
  • Unigene: 433863 Human
  • Unigene: 195898 Mouse
  • Unigene: 338476 Mouse
  • Unigene: 473809 Mouse
  • Unigene: 29745 Rat

  see all

• Alternative names
  HCNP antibodyHCNPpp antibodyHippocampal cholinergic neurostimulating peptide antibody

  Neuropolypeptide h3 antibodyPEBP antibodyPEBP 1 antibodyPEBP-1 antibodyPebp1 antibodyPEBP1_HUMAN antibodyPhosphatidylethanolamine Binding Protein antibodyPhosphatidylethanolamine binding protein 1 antibodyProstatic Binding Protein antibodyProstatic-binding protein antibodyR kip antibodyRaf kinase inhibitor protein antibodyRaf kinase inhibitory protein antibodyRKIP antibody

  see all

Anti-PBP antibody images

• 

  Western blot - PBP antibody (ab2634)
  
  
  Predicted band size : 22 kDa
  
  
  ab2634 staining (0.01 µg/ml) of A549 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PBP antibody (ab2634)
  ab2634 (1.5 µg/ml) staining PBP in paraffin-embedded Human Cortex following steamed antigen retrieval with citrate buffer at pH 6.