Overview
- Product nameAnti-Amphiregulin antibody - BSA and Azide freeSee all Amphiregulin primary antibodies ...
- DescriptionRabbit polyclonal to Amphiregulin - BSA and Azide free
- SpecificityHighly specific to amphiregulin. No cross-reactivity with EGF, TGFa, or HB-EGF.
- Tested applicationsWB, IP more details
- Species reactivityReacts with: Mouse, Human
- Immunogen
Synthetic peptide: RKKKGGKNGKNRRNRKKKN, corresponding to amino acids 26-44 of secreted Human Amphiregulin
- Positive controlLS174T; phorbol ester treated MCF-7 breast cancer cells; epithelial cells of mucosal surface in normal colon.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C (add glycerol to a final volume of 50% for extra stability). Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 10mM PBS, pH 7.4 -
Concentration information loading... - PurityProtein A purified
- Primary antibody notes Directed against the region of amphiregulin which binds to heparin.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab31344 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 5 µg/ml. Predicted molecular weight: 28 kDa. |
| IP | IP: Use at an assay dependent dilution. |
Target
- FunctionBifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.
- Sequence similaritiesBelongs to the amphiregulin family.
Contains 1 EGF-like domain. - Cellular localizationMembrane.
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Database links
- Entrez Gene: 374 Human
- Entrez Gene: 727738 Human
- Entrez Gene: 11839 Mouse
- Omim: 104640 Human
- SwissProt: P15514 Human
- SwissProt: Q4FJT2 Mouse
- SwissProt: P31955 Mouse
- Unigene: 270833 Human
- Unigene: 645475 Human
- Unigene: 8039 Mouse
see all
Target information above from: UniProt accession
P15514
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- A REG antibodyAmphiregulin antibodyAR antibody
- AR antibodyAREG antibodyAREG_HUMAN antibodyAREGB antibodyColorectum cell derived growth factor antibodyColorectum cell derived growth factor antibodyColorectum cell-derived growth factor antibodyCRDGF antibodyCRDGF antibodyMGC13647 antibodySchwannoma derived growth factor antibodySDGF antibody
see all
References for Anti-Amphiregulin antibody - BSA and Azide free (ab31344)
ab31344 has not yet been referenced specifically in any publications.
