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This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

  • Product nameAnti-LD78 beta antibodySee all LD78 beta primary antibodies ...
  • Description
    Goat polyclonal to LD78 beta

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • SpecificityThis product is expected to recognize the products of 2 different genes which are almost identical.
  • Species reactivity

    Predicted to work with: Human, Chimpanzee
  • Immunogen

    Synthetic peptide: EWVQKYVSDLELSA, corresponding to C terminal amino acids 80-93 of Human LD78 beta

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline. pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

  • Application notesThis antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionChemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
    • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications      The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
    • Cellular localizationSecreted.

      • Target information above from: UniProt accession P16619 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          464.2 antibodyC C motif chemokine 3 like 1 antibodyCCL3L1 antibody
          CCL3L3 antibodyChemokine (C C motif) ligand 3 like 1 antibodyChemokine (C C motif) ligand 3 like 3 antibodyChemokine (C C motif) ligand 3 like, centromeric antibodychemokine (CC motif) ligand 3 like 1 antibodyCL3L1_HUMAN antibodyD17S1718 antibodyG0/G1 switch regulatory protein 19-2 antibodyG0S19-2 antibodyLD78 antibodyLD78 beta(1-70) antibodyLD78-beta(1-70) antibodyLD78-beta(5-70) antibodyLD78BETA antibodyMGC104178 antibodyMGC12815 antibodyMGC182017 antibodyMIP1AP antibodyPAT 464.2 antibodySCYA3L antibodySCYA3L1 antibodySmall inducible cytokine A3 like 1 precursor antibodySmall-inducible cytokine A3-like 1 antibodyTonsillar lymphocyte LD78 beta antibodyTonsillar lymphocyte LD78 beta protein antibody
        see all

      References for Anti-LD78 beta antibody (ab36129)

      ab36129 has not yet been referenced specifically in any publications.

      Publishing research using ab36129 ? Please let us know so that we can cite the reference in this datasheet

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"