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| Product Name | MMP17 antibody - Aminoterminal end |
| | See all MMP17 antibodies (6)... |
| Product type | Primary antibodies |
| Description | Rabbit polyclonal to MMP17 - Aminoterminal end |
| Immunogen | Synthetic peptide from Human MMP17 corresponding to the aminoterminal end.
(Peptide available as ab41102.) |
| Reacts with
(species key) | Hu |
| Specificity | This antibody binds to the aminoterminal end of active MMP17. It can recognize native or reduced MMP17, but does not cross react with the other MMP family members (MMP1, MMP2, MMP3, MMP9,etc.). We have a range of domain specific antibodies for this target. For a full list please see all MMP17 antibodies |
| Tested applications
(see key) | WB |
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| Abreviews | |
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| Application notes
(see key) | Recommended dilutions
WB: 1/1000 when using colorimetric substrates such as BCIP/NBT - 1/5000 when using chemiluminescent substrates. Predicted molecular weight: 67 kDa. When used against the reduced protein, ab39028 identifies bands at 65 kD and 63 kD (the pro-form and active form), as well as activation/breakdown products. Note: Treatment of cells with Concanavolin-A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Cellular localization | Cell membrane; lipid anchor; GPI anchor; extracellular side.
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| Research areas | Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> MMPs
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> MMPs
Cancer >> Invasion/microenvironment >> |
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