| · Glycerol MSDS · Sodium Azide MSDS | |
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| Product Name | MMP20 antibody - Hinge region |
| | See all MMP20 antibodies (4)... |
| Product type | Primary antibodies |
| Description | Rabbit polyclonal to MMP20 - Hinge region |
| Immunogen | Synthetic peptide based on the hinge region of the human MMP20 sequence.
(Peptide available as ab41110.) |
| Reacts with
(species key) | Hu |
| Specificity | This antibody is specific for MMP20, but does not cross react with the other MMP family members (MMP-1, MMP-2, MMP-3, MMP-9, etc.). We have a range of domain specific antibodies for this target. For a full list please see all MMP20 antibodies |
| Tested applications
(see key) | WB |
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| Abreviews | |
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| Application notes
(see key) | Recommended dilutions
WB: 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates. Detects bands of approximately 58kDa and 45kDa and a series of further cleaved active forms (predicted molecular weight: 58 kDa). Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Cellular localization | Secreted; extracellular space; extracellular matrix. |
| Research areas | Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> MMPs
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> MMPs
Cancer >> Invasion/microenvironment >> Angiogenesis >> ECM enzymes >> MMPs
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP |
| Relevance | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
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| Database links | The links below go to external sites and will open in a new browser window |
| Raised in | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Immunogen affinity purified |
| Storage buffer | Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
|
| Form | Liquid |
| Concentration | 1.000 mg/ml |
| Storage instructio |
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