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| | Western blot - DPP10 antibody - Stalk region (ab42082)
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| Product Name | DPP10 antibody - Stalk region |
| | See all DPP10 antibodies (6)... |
| Product type | Primary antibodies |
| Description | Rabbit polyclonal to DPP10 - Stalk region |
| Immunogen | Synthetic peptide corresponding to the stalk region of human DPP10.
(Peptide available as ab44601.) |
| Reacts with
(species key) | Hu, Ms, Rat |
| Specificity | This antibody recognises all four forms of DPP10. This antibody does not recognise other DPP family members We have a range of domain specific antibodies for this target. For a full list please see all DPP10 antibodies |
| Tested applications
(see key) | WB |
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| Abreviews | |
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| Application notes
(see key) | Recommended dilutions
WB: 1/1000 - 1/5000. Predicted molecular weight: 91 kDa. Recommended starting dilution 1/1000 for use with colourimetric substrates, 1/5000 for use with chemiluminescent substrates. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Cellular localization | Type II membrane protein. |
| Research areas | Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> DPPs
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| Relevance | A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma. |
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| Database links | The links below go to external sites and will open in a new browser window |
| Raised in | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Immunogen affinity purified |
| Storage buffer | Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 0.5M Sodium chloride Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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| Form | Liquid |
| Concentration | 1.000 mg/ml |
| Storage instructions | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this DPP10 antibody - Stalk region is on this datasheet. But please do contact us if you would like any reassurance! |
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| See below for DPP10 antibody - Stalk region images, references, products related to ab42082 and other tools. |
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DPP10 antibody - Stalk region images: |
 Western blot - DPP10 antibody - Stalk region (ab42082)
All lanes : DPP10 antibody - Stalk region (ab42082) at 1/1000 dilution
Lane 1 : Cell Line DU 145 SF treated
Lane 2 : Cell Line DU 145 RA treated
Predicted band size : 91 kDa
Observed band size : 96 kDa (why is the actual band size different from the predicted?)
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| Search PubMed (MEDLINE) for references to DPP10 |
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