Overview
Product nameDAB2 peptide (758-770)See all DAB2 proteins and peptides ...
Protein descriptionSynthetic peptide: C-SEMYRDPFGNPFA, corresponding to C terminal amino acids 758-770 of Human DAB2.
This peptide was used as an immunogen for ab20468 - DAB2 antibody.
Properties
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration information loading...
SequenceC-SEMYRDPFGNPFA
Research Areas
Protein info
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Alternative names
DAB 2DAB2Differentially expressed protein 2
Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein)disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)Disabled homolog 2Disabled homolog 2 mitogen responsive phosphoproteinDisabled homolog 2 mitogen responsive phosphoprotein (Drosophila)disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila)DOC 2DOC2FLJ26626Mitogen responsive phosphoprotein
see all
RelevanceDAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).
Cellular localizationCytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit.
Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.
References for DAB2 peptide (758-770) (ab45512)
ab45512
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"