ADAM12 peptide (2-15) (ab45636)
- A disintegrin and metalloproteinase domain 12A disintegrin and metalloproteinase domain 12ADA12_HUMAN
- ADAM 12ADAM metallopeptidase domain 12ADAM12Disintegrin and metalloproteinase domain-containing protein 12MCMPMCMPMltnaMCMPMltnaMeltrin alphaMeltrin-alphaMLTNMLTNAOTTHUMP00000046766
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsThe precursor is cleaved by a furin endopeptidase.
References for ADAM12 peptide (2-15) (ab45636)
ab45636 has not yet been referenced specifically in any publications.