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IL2 Murine Elipair Kit (Reagents provided for 10 x 96 Well Plates) (ab47592)

Overview

  • Product nameIL2 Murine Elipair Kit (Reagents provided for 10 x 96 Well Plates)See all IL2 kits ...
  • Tests
    10 x 96 well plate
  • Sample type
    Cell culture supernatant, Serum, Plasma
  • Assay typeELIPAIR
  • Sensitivity
    < 5 pg/ml
  • Range
    15.6 pg/ml - 500 pg/ml
  • Assay durationMultiple steps standard assay
  • Species reactivity
    Reacts with: Mouse
  • Product overview

    The murine IL-2 Eli-pair includes both the capture and the detection antibodies as well as Horse-Radish peroxidase conjugated Streptavidin (HRP-Strep) and TMB which are the reagents used in the colour development step.

    This Eli-pair set is intended to measure murine IL-2 in cell -culture supernatants, as well as in serum samples. The enclosed procedures provide general guidelines for ELISA preparation. This procedure may need some optimization depending on the plastic, matrix, standard range.

     

    Recognizes both natural and recombinant Murine IL2

  • Tested applicationsEli-pair more details
  • PlatformReagents

Properties

  • FunctionProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • Involvement in diseaseNote=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • Sequence similaritiesBelongs to the IL-2 family.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession P60568 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
    • Alternative names
        AldesleukinIL 2IL-2
        IL2IL2_HUMANInterleukin-2lymphokineT cell growth factorT-cell growth factorTCGF
      see all
  • Database links
  • Applications

    Our Abpromise guarantee covers the use of ab47592 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Eli-pair EliP

    IL2 Murine Elipair Kit (Reagents provided for 10 x 96 Well Plates) images

    • Murine IL2 Standard curve ranging from 15.6 to 500 pg/mL

    References for IL2 Murine Elipair Kit (Reagents provided for 10 x 96 Well Plates) (ab47592)

    ab47592 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"