Overview
Product nameHSV1 gD proteinSee all HSV1 gD proteins and peptides ...
Protein descriptionRecombinant protein containing the HSV-1 gD immunodominant regions, amino acids 84-175.
Expression hostE. coli
Properties
Purification notesPurified.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab48970
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| ELISA |
ELISA: Use at an assay dependent dilution. |
| WB |
WB: Use at an assay dependent dilution. |
Protein info
-
Alternative names
GDGlycoprotein DHerpes simplex virus type 1 glycoprotein D
see all
RelevanceHerpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
References for HSV1 gD protein (ab48970)
ab48970
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
