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Overview

  • Product nameFGF4 proteinSee all FGF4 proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 25/206 of Human FGF4 with sequence GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Concentration information loading...
  • Sequence notesGRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab50131 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution. The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/mg.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab135686.

    • Protein info

    • Alternative names
        FGF-4Fgf4FGF4_HUMAN
        Fibroblast growth factor 4HBGF-4HBGF4Heparin secretory-transforming protein 1Heparin-binding growth factor 4HstHST-1HST1HSTF-1HSTF1Human stomach cancer transforming factor from FGF related oncogeneK FGFKaposi Sarcoma OncogeneKFGFKS3Oncogene HSTTransforming protein KS3
      see all
  • FunctionCan transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity.
  • Sequence similaritiesBelongs to the heparin-binding growth factors family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P08620 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for FGF4 protein (ab50131)

    ab50131 has not yet been referenced specifically in any publications.

    Publishing research using ab50131 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"