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Overview

  • Product nameAnti-CD244 antibody [2B4.69]See all CD244 primary antibodies ...
  • Description
    Mouse monoclonal [2B4.69] to CD244
  • Specificityab54254 is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
  • Tested applicationsIP, Flow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CD244 Fusion protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab54254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IP
Flow Cyt
  • Application notesFlow Cyt: 1/50 - 1/200.
    Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
    IP: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionModulate other receptor-ligand interactions to enhance leukocyte activation.
    • Tissue specificityExpressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.
    • Sequence similaritiesContains 2 Ig-like (immunoglobulin-like) domains.
    • Cellular localizationMembrane.

      • Target information above from: UniProt accession Q9BZW8 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          2B4 antibodyC9.1 antibodyCD244 antibody
          CD244 antigen antibodyCD244 molecule natural killer cell receptor 2B4 antibodyCD244 natural killer cell receptor 2B4 antibodyCD244_HUMAN antibodyF730046O15Rik antibodyh2B4 antibodyLy90 antibodyNAIL antibodyNatural killer cell activation-inducing ligand antibodyNatural killer cell receptor 2B4 antibodyNK cell activation inducing ligand antibodyNK cell activation inducing ligand NAIL antibodyNK cell activation-inducing ligand antibodyNK cell type I receptor protein 2B4 antibodyNKR2B4 antibodyNmrk antibodyNon-MHC restricted killing associated antibodyOTTHUMP00000027884 antibodyp38 antibodySLAM family, member 4 antibodySLAMF4 antibody
        see all

      References for Anti-CD244 antibody [2B4.69] (ab54254)

      This product has been referenced in:
      • Ghio M  et al. Soluble HLA-I-mediated secretion of TGF-beta1 by human NK cells and consequent down-regulation of anti-tumor cytolytic activity. Eur J Immunol 39:3459-68 (2009). Flow Cyt ; Human . Read more (PubMed: 19830740) »

      See 1 Publication for this product

      Publishing research using ab54254 ? Please let us know so that we can cite the reference in this datasheet

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"