Anti-CIDE A antibody (ab54630)

Overview

• Product nameAnti-CIDE A antibodySee all CIDE A primary antibodies ...
• Description
  Mouse monoclonal to CIDE A
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Recombinant Fragment
  Predicted to work with: Human
• Immunogen

  Recombinant full length protein, corresponding to amino acids 1-254 of Human CIDE A

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  PBS, pH 7.2
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• IsotypeIgG2a
• Light chain typekappa
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Fatty acid oxidation

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Apoptosis

  • Cardiovascular
  • Heart
  • Apoptosis

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Metabolism

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Apoptosis
  • Nuclear

  • Cell Biology
  • Apoptosis
  • Nucleus
  • DNAses

Applications

Target

• RelevanceApoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICARD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B (for cell death inducing DFF like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE A is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE A is expressed in many tissues.
• Cellular localizationNuclear. Cytoplasm; mitochondrial envelope; lipid droplet.
• Database links
  • Entrez Gene: 1149 Human
  • Omim: 604440 Human
  • SwissProt: O60543 Human
  • Unigene: 249129 Human

• Alternative names
  Cell death activator CIDE A antibodyCell Death Inducing DFFA Like Effector A antibodycell death inducing DNA fragmentation factor, alpha subunit like effector A antibody

  CIDE-A antibodyCIDEA antibody

  see all

Anti-CIDE A antibody images

• 

  Western blot - CIDE A antibody (ab54630)
  Western blot against tagged recombinant protein immunogen using ab54630 CIDE A antibody at 1ug/ml. Predicted band size of immunogen is 54 kDa.

  This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.