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Anti-BMP7 antibody (ab54904)

Abreviews (1)Q&A (1)

Overview

  • Product nameAnti-BMP7 antibodySee all BMP7 primary antibodies ...
  • Description
    Mouse monoclonal to BMP7
  • Tested applicationsWB, ICC/IF more details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-432 of Human BMP7

Properties

Applications

Our Abpromise guarantee covers the use of ab54904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
ICC/IF
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionInduces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    • Tissue specificityExpressed in the kidney and bladder. Lower levels seen in the brain.
    • Sequence similaritiesBelongs to the TGF-beta family.
    • Developmental stageExpressed in the developing eye, brain and ear during embryogenesis.
    • Post-translational
      modifications      Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    • Cellular localizationSecreted.

      • Target information above from: UniProt accession P18075 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      see all
    • Alternative names
        BMP 7 antibodyBMP-7 antibodyBmp7 antibody
        BMP7_HUMAN antibodyBone morphogenetic protein 7 antibodyBone morphogenic protein 7 antibodyEptotermin alfa antibodyOP 1 antibodyOP-1 antibodyOP1 antibodyOsteogenic protein 1 antibody
      see all

    Anti-BMP7 antibody images

    • Western blot - BMP7 antibody (ab54904)
      Western blot - BMP7 antibody (ab54904)


      Predicted band size : 49 kDa
      BMP7 antibody (ab54904) at 1ug/lane + Raw cell lysate at 25ug/lane.
    • Immunocytochemistry/ Immunofluorescence - Anti-BMP7 antibody (ab54904)
      Immunocytochemistry/ Immunofluorescence - Anti-BMP7 antibody (ab54904)This image was taken from an abreview submitted by Ruma Raha-Chowdhury.
      ICC/IF image of ab54904 staining of BMP7 in rat primary hippocampal neuron culture. The sections were incubated in 0.3% triton X to permeabilise the cells and in 10% serum to block non-specific protein-protein interactions. The sections were incubated with ab54904 (1:1000) overnight at +4°C, followed by a second incubation with Alexa 488 conjugated secondary antibody. BMP7 (green staining) is observed in the pyramidal cells of the hippocampus.

      See Abreview

    References for Anti-BMP7 antibody (ab54904)

    ab54904 has not yet been referenced specifically in any publications.

    Publishing research using ab54904 ? Please let us know so that we can cite the reference in this datasheet

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    Cusotmer kindly contacted us to ask if these products has been tested against other BMP proteins.

    Thank you for contacting us.



    We haven’t tested this antibody for other BMP proteins.However, we have run blast with other BMP proteins.



    The similarity with BMP4 transcript variant 1/2/3 are all lower tha...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"