Overview
- Product nameAnti-Bag5 antibodySee all Bag5 primary antibodies ...
- DescriptionMouse monoclonal to Bag5
- Tested applicationsWB more details
- Species reactivityReacts with: Human
- Immunogen
Recombinant full length protein, corresponding to amino acids 1-448 of Human Bag5
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
PBS, pH 7.2 -
Concentration information loading... - PurityProtein G purified
- Clonality Monoclonal
- IsotypeIgG1
- Light chain typekappa
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab56738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB |
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionInhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
- Sequence similaritiesContains 5 BAG domains.
- DomainThe fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
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Database links
- Entrez Gene: 9529 Human
- Entrez Gene: 9529 Human
- Omim: 603885 Human
- SwissProt: Q9UL15 Human
- SwissProt: Q9UL15 Human
- Unigene: 5443 Human
Target information above from: UniProt accession
Q9UL15
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- BAG family molecular chaperone regulator 5 antibodyBAG-5 antibodyBAG5 antibody
- BAG5_HUMAN antibodyBcl-2-associated athanogene 5 antibodyBCL2 associated athanogene 5 antibodyKIAA0873 antibody
see all
Anti-Bag5 antibody images
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Western blot - Bag5 antibody (ab56738)
Predicted band size : 51 kDa
Bag5 antibody (ab56738) at 1ug/lane + Jurkat cell lysate at 25ug/lane.
References for Anti-Bag5 antibody (ab56738)
This product has been referenced in:
- Boiani M et al. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem 288:6980-90 (2013). WB ; Human . Read more (PubMed: 23341456) »
- Gong C & Maquat LE lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 470:284-8 (2011). WB ; Human . Read more (PubMed: 21307942) »
