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Overview

  • Product nameAnti-Apc2 antibodySee all Apc2 primary antibodies ...
  • Description
    Mouse monoclonal to Apc2
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 716-823 of Human Apc2

Properties

Applications

Our Abpromise guarantee covers the use of ab57094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesBelongs to the cullin family.

      • Target information above from: UniProt accession Q9UJX6 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          anapc2 antibodyAnaphase promoting complex subunit 2 antibodyAnaphase-promoting complex subunit 2 antibody
          ANC2_HUMAN antibodyAPC2 antibodyCyclosome subunit 2 antibodyKIAA1406 antibodyOTTHUMP00000022692 antibodyRP11 350O14.5 antibody
        see all

      Anti-Apc2 antibody images

      • Western blot - Apc2 antibody (ab57094)
        Western blot - Apc2 antibody (ab57094)
        Western blot against tagged recombinant protein immunogen using ab57094 Apc2 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

      References for Anti-Apc2 antibody (ab57094)

      ab57094 has not yet been referenced specifically in any publications.

      Publishing research using ab57094 ? Please let us know so that we can cite the reference in this datasheet

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"