Overview
- Product nameAnti-CHRDL1 antibodySee all CHRDL1 primary antibodies ...
- DescriptionMouse monoclonal to CHRDL1
- Tested applicationsWB more details
- Species reactivityReacts with: Human
- Immunogen
Recombinant fragment, corresponding to amino acids 347-457 of Human CHRDL1
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
PBS, pH 7.2 -
Concentration information loading... - PurityProtein G purified
- Clonality Monoclonal
- IsotypeIgG1
- Light chain typekappa
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab57933 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB |
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionAntagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
- Tissue specificityExpressed in retinal pericytes.
- Sequence similaritiesContains 3 VWFC domains.
- Cellular localizationSecreted.
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Database links
- Entrez Gene: 91851 Human
- Entrez Gene: 91851 Human
- Entrez Gene: 91851 Human
- Omim: 300350 Human
- SwissProt: Q9BU40 Human
- SwissProt: Q9BU40 Human
- SwissProt: Q9BU40 Human
- Unigene: 496587 Human
Target information above from: UniProt accession
Q9BU40
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- CHL antibodychordin like 1 antibodyChordin-like protein 1 antibody
- CHRDL1 antibodyCRDL1_HUMAN antibodydA141H5.1 antibodyneuralin 1 antibodyNeuralin-1 antibodyNeurogenesin-1 antibodyNRLN1 antibodyVentroptin antibodyVOPT antibody
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Anti-CHRDL1 antibody images
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Western blot - CHRDL1 antibody (ab57933)
Predicted band size : 51 kDa
CHRDL1 antibody (ab57933) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-CHRDL1 antibody (ab57933)
ab57933 has not yet been referenced specifically in any publications.
