Anti-SOX4 antibody [154C4a] - ChIP Grade (ab70598)

Overview

• Product nameAnti-SOX4 antibody [154C4a] - ChIP GradeSee all SOX4 primary antibodies ...
• Description
  Mouse monoclonal [154C4a] to SOX4 - ChIP Grade
• Tested applicationsChIP, WB, Dot Blot more details
• Species reactivity
  Reacts with: Mouse, Recombinant Fragment
  
• Immunogen

  Recombinant fragment of human SOX4 from an internal sequence.

• Positive controlRecombinant human SOX4.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.05% Sodium Azide
  Constituents: 1% BSA, PBS pH 7.4
• Concentration information loading...
• PurityProtein G purified
• Purification notesab70598 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
• Clonality Monoclonal
• Clone number154C4a
• IsotypeIgG2a
• Research Areas
  • Stem Cells
  • Neural Stem Cells
  • Intracellular

  • Epigenetics and Nuclear Signaling
  • ChIP'ing antibodies
  • ChIP'ing antibodies

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • HMG Box

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • Developmental Families
  • Other

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

  • Neuroscience
  • Cell Type Marker
  • Neural Stem Cell marker

Applications

Target

• RelevanceThe SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. SOX4 shows a high degree of sequence homology with SOX11. Both are expressed in the CNS. SOX4 and SOX11 expression increase together in the developing CNS (with some exceptions: external granule layer of the cerebellum). SOX4 knock-out mice have been shown to die of a heart defect half way through gestation with no observable CNS phenotype, although it has been proposed that SOX11 compensates for the absence of SOX4.
• Cellular localizationNuclear
• Database links
  • Entrez Gene: 20677 Mouse
  • SwissProt: Q06831 Mouse
  • Unigene: 240627 Mouse

• Alternative names
  Ecotropic viral integration site 16 antibodyEVI 16 antibodyEVI16 antibody

  SRY (sex determining region Y) box 4 antibodySRY box containing gene 4 antibodySRY related HMG box gene 4 antibody

  see all

Anti-SOX4 antibody [154C4a] - ChIP Grade images

• 

  Western blot - SOX4 antibody [154C4a] (ab70598)
  Anti-SOX4 antibody [154C4a] - ChIP Grade (ab70598) + immunising recombinant protein
  
  Predicted band size : 47 kDa
  Observed band size : 38 kDa (why is the actual band size different from the predicted?)