Anti-Transferrin antibody (ab82411)
Key features and details
- Rabbit polyclonal to Transferrin
- Suitable for: IP, ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Guinea pig, Dog, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Transferrin antibody
See all Transferrin primary antibodies -
Description
Rabbit polyclonal to Transferrin -
Host species
Rabbit -
Tested applications
Suitable for: IP, ICC/IF, IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Guinea pig, Dog, Human -
Immunogen
Full length protein corresponding to Human Transferrin.
Database link: P02787 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab82411 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IP |
Use at an assay dependent concentration.
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ICC/IF | (3) |
Use at an assay dependent concentration.
|
IHC-P |
Use at an assay dependent concentration.
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|
WB | (4) |
1/10000. Predicted molecular weight: 77 kDa.
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Notes |
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IP
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
1/10000. Predicted molecular weight: 77 kDa. |
Target
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Function
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Involvement in disease
Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. -
Sequence similarities
Belongs to the transferrin family.
Contains 2 transferrin-like domains. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 7018 Human
- Entrez Gene: 22041 Mouse
- Entrez Gene: 24825 Rat
- Omim: 190000 Human
- SwissProt: P02787 Human
- SwissProt: Q921I1 Mouse
- SwissProt: P12346 Rat
- Unigene: 518267 Human
see all -
Alternative names
- Apotransferrin antibody
- Beta 1 metal binding globulin antibody
- Beta-1 metal-binding globulin antibody
see all
Images
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Anti-Transferrin antibody (ab82411) at 1/10000 dilution + rat apotransferrin
Developed using the ECL technique.
Predicted band size: 77 kDa
Observed band size: 77 kDa -
Anti-Transferrin antibody (ab82411) at 1/1000 dilution + Mouse pancreatic acinar cells at 30 µg with Milk, 12 hours, 4°C at 5 %
Secondary
Goat anti-rabbit IgG (HRP conjugated) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 77 kDa
Exposure time: 10 minutes
Datasheets and documents
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SDS download
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Datasheet download
References (50)
ab82411 has been referenced in 50 publications.
- Zeng F et al. Glutathione S-transferase kappa 1 is positively related with sperm quality of porcine sperm. Mol Reprod Dev 89:104-112 (2022). PubMed: 34888969
- Chakravarty D et al. Systemic deficiency of vitronectin is associated with aortic inflammation and plaque progression in ApoE-Knockout mice. FASEB Bioadv 4:121-137 (2022). PubMed: 35141476
- Zhang R et al. Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis. Bioact Mater 13:23-36 (2022). PubMed: 35224289
- Wang Y et al. Comparison of the Chemical Components, Efficacy and Mechanisms of Action of Chrysanthemum morifolium Flower and Its Wild Relative Chrysanthemum indicum Flower against Liver-Fire Hyperactivity Syndrome of Hypertension via Integrative Analyses. Int J Mol Sci 23:N/A (2022). PubMed: 36430265
- Courelli V et al. Digestive Enzyme Activity and Protein Degradation in Plasma of Heart Failure Patients. Cell Mol Bioeng 14:583-596 (2021). PubMed: 34900012