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Overview

  • Product nameIL13 protein (Active)See all IL13 proteins and peptides ...
  • Protein descriptionRecombinant full length bovine IL13 (amino acids 21-132), expressed in Yeast. Predicted MWt 12.6 kDa (Swiss-Prot Q9XSV9).
  • Expression hostYeast

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab87383 is purified by Ion-exchange chromatography.
  • Biological activityThe biological activity of recombinant bovine IL13 was measured in a cell proliferation assay using the human TF1 cell line. The ED50 for this effect is typically 20 - 30 ng/mL.
  • FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°CThis product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1.0X PBS
  • Concentration information loading...
  • Sequence notesSPVPSATALK ELIEELVNIT QNQKVPLCNG SMVWSLNLTS SMYCAALDSL ISISNCSVIQ RTKRMLNALC PHKPSAKQVS SEYVRDTKIE VAQFLKDLLR HSRIVFRNER FN
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab87383 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Cellular activation CellAct: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        Allergic rhinitisALRHBHR1
        Bronchial hyperresponsiveness 1 (bronchial asthma)IL 13IL-13Il13IL13_HUMANInterleukin 13Interleukin-13MGC116786MGC116788MGC116789NC30P600
      see all
  • FunctionCytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
  • Involvement in diseaseDefects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
  • Sequence similaritiesBelongs to the IL-4/IL-13 family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P35225 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for IL13 protein (Active) (ab87383)

    ab87383 has not yet been referenced specifically in any publications.

    Publishing research using ab87383 ? Please let us know so that we can cite the reference in this datasheet

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