SCF protein (Active) (ab88278)
Constituents: 0.7M Sodium chloride, 30mM Sodium acetate, pH 4.5
Our Abpromise guarantee covers the use of ab88278 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution. As a result of glycosylation, the recombinant protein migrates as three bands with an apparent molecular mass of 24, 23, 21 kDa in SDS-PAGE.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- C kit ligandC-kit ligandCkit ligand
- DKFZp686F2250familial progressive hyperpigmentation 2FPH2KIT ligandKitlKITLGKL 1KL1Mast cell growth factorMGFSCFSCF_HUMANSFSHEP7sKITLGSoluble KIT ligandSteel factorStem cell factorStem cell factor precursor
modificationsA soluble form (sKITLG) is produced by proteolytic processing of isoform 1 in the extracellular domain.
Found in two differentially glycosylated forms, LMW-SCF and HMW-SCF. LMW-SCF is fully N-glycosylated at Asn-145, partially N-glycosylated at Asn-90, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97 or Asn-118. HMW-SCF is N-glycosylated at Asn-118, Asn-90 and Asn-145, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97.
A soluble form exists as a cleavage product of the extracellular domain.
References for SCF protein (Active) (ab88278)
ab88278 has not yet been referenced specifically in any publications.