Anti-ADRM1 antibody (ab91567)

Overview

• Product nameAnti-ADRM1 antibodySee all ADRM1 primary antibodies ...
• Description
  Rabbit polyclonal to ADRM1
• Tested applicationsIP, WB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide, corresponding to a region within amino acids 357-407 of Human ADRM1 (NP_008933.2).

• Positive controlHeLa and 293T whole cell lysates.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: Tris citrate/phosphate, pH 7-8
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab91567 was affinity purified using an epitope specific to ADRM1 immobilized on solid support.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cell Adhesion
  • Cell Adhesion Molecules
  • Endothelial

Applications

Target

• FunctionFunctions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.
• Sequence similaritiesBelongs to the ADRM1 family.
  Contains 1 PH domain.
• DomainThe PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit of K48-linked diubiquitin allows UCHL5 access to the distal subunit.
• Cellular localizationCytoplasm. Nucleus.

Target information above from: UniProt accession Q16186 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 11047 Human
  • Omim: 610650 Human
  • SwissProt: Q16186 Human
  • Unigene: 90107 Human

• Alternative names
  110 kDa cell membrane glycoprotein antibodyadhesion regulating molecule 1 antibodyAdhesion-regulating molecule 1 antibody

  ADRM 1 antibodyADRM1 antibodyADRM1_HUMAN antibodyARM 1 antibodyARM-1 antibodyARM1 antibodyGP110 antibodyhRpn13 antibodyM(r) 110,000 surface antigen antibodyProteasomal ubiquitin receptor ADRM1 antibodyproteasome regulatory particle non ATPase 13 antibodyProteasome regulatory particle non-ATPase 13 antibodyRegulatory particle non ATPase 13 antibodyRpn13 antibodyRpn13 homolog antibody

  see all

Anti-ADRM1 antibody images

• 

  Western blot - ADRM1 antibody (ab91567)
  All lanes : Anti-ADRM1 antibody (ab91567) at 0.1 µg/ml
  
  Lane 1 : HeLa whole cell lysate at 50 µg
  Lane 2 : HeLa whole cell lysate at 15 µg
  Lane 3 : HeLa whole cell lysate at 5 µg
  Lane 4 : 293T whole cell lysate at 50 µg
  
  developed using the ECL technique
  
  Predicted band size : 42 kDa
  
  
  Exposure time : 3 minutes
• 

  Immunoprecipitation - ADRM1 antibody (ab91567)
  Detection of ADRM1 by Western Blot of Immunprecipitate.
  ab91567, at 1 µg/ml, staining ADRM1 in HeLa whole cell lysate immunoprecipitated using ab91567 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
  Detection: Chemiluminescence with exposure time of 30 seconds.