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Overview

  • Product nameSTATIP1 protein (Tagged-His Tag)
  • Protein descriptionRecombinant fragment, corresponding to amino acids 552-826 (275 amino acids) of Human STATIP1 with an N terminal His tag. 34 kDa (Predicted mwt: 32 kDa); UniProt ID: Q6IA86.
  • Expression hostE. coli

    • Properties

  • Purification notesPurity level >85%
    This protein was expressed as an N-terminal His-tag fusion protein using Escherichia coli, and purified using Immobilized Metal Ion Affinity Chromatography. In some cases, smaller protein fragments may be present in addition to the intended expression product as a result of premature termination during translation in E. coli and subsequent co-purification via the His-tag. In some cases purified proteins run at a molecular weight different to the theoretically calculated molecular weight. This may be as a result of unequally distributed charges in the amino acid sequence. Alternatively, dimerisation of the expression product can occur under oxygen limitation during expression/cultivation.
  • FormLyophilised:Reconstitute with 163 µl distilled water.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
  • Concentration information loading...
  • Sequence notesLQNTLWPEVQKLYGHGYEIFCVTCNSSKTLLASACKAAKK EHAAIILWNTTSWKQVQN LVFHSLTVTQMAFSPNEKFL LAVSRDRTWSLWKKQDTISPEFEPVFSLFAFTNKITSV HSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECDSTDDCIE HNIGPCSSVLDVGGAVTA VSVCPVLHPSQRYVVAVGLE CGKICLYTWKKTDQVPEINDWTHCVETSQSQSHTLAIR KLCWKNCSGKTEQKEAEGAEWLHFASCGEDHTVKIHRVNK CAL
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab92030 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE
  • Application notesSDS-PAGE: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        AU023723Elongation protein 2 homolog (S. cerevisiae)Elongator complex protein 2
        elongator protein 2ELP2ELP2_HUMANEpl2FLJ10879SHINC 2SHINC-2SHINC2signal transducer and activator of transcription 3 interacting protein 1signal transducer and activator of transcription interacting protein 1Stat3 interacting proteinSTAT3 interacting protein 1STAT3-interacting protein 1STATIP 1STATIP1STATIP1 proteinStIPStIP1
      see all
  • FunctionRegulates the ligand-dependent activation of STAT3.
    Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
  • Sequence similaritiesBelongs to the WD repeat ELP2 family.
    Contains 14 WD repeats.
  • Cellular localizationCytoplasm. Nucleus.

    • Target information above from: UniProt accession Q6IA86 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    STATIP1 protein (Tagged-His Tag) images

    • SDS-PAGE - STATIP1 protein (Tagged-His Tag) (ab92030)
      SDS-PAGE - STATIP1 protein (Tagged-His Tag) (ab92030)
      The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

    References for STATIP1 protein (Tagged-His Tag) (ab92030)

    ab92030 has not yet been referenced specifically in any publications.

    Publishing research using ab92030 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"