Overview
- Product nameAnti-HB9/HLXB9 antibodySee all HB9/HLXB9 primary antibodies ...
- DescriptionRabbit polyclonal to HB9/HLXB9
- Tested applicationsWB, IHC-P more details
- Species reactivityReacts with: Mouse, Rat, Human
Predicted to work with: Dog
- Immunogen
Synthetic peptide, corresponding to a portion of amino acids 330 - 380 of Mouse HB9/HLXB9 (NP_064328.2).
- Positive controlWB: MOLT 4 cell lysate; IHC-P: Mouse pancreas tissue.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 0.05% BSA, PBS -
Concentration information loading... - PurityProtein A purified
- Clonality Polyclonal
- IsotypeIgG
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab92606 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | |
| IHC-P |
WB: Use at a concentration of 0.5 - 2.0 µg/ml. Predicted molecular weight: 41 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionPutative transcription factor involved in pancreas development and function.
- Tissue specificityExpressed in lymphoid and pancreatic tissues.
- Involvement in diseaseDefects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
- Sequence similaritiesContains 1 homeobox DNA-binding domain.
- Cellular localizationNucleus.
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Database links
- Entrez Gene: 3110 Human
- Entrez Gene: 15285 Mouse
- Omim: 142994 Human
- SwissProt: P50219 Human
- SwissProt: Q9QZW9 Mouse
- Unigene: 37035 Human
- Unigene: 103760 Mouse
Target information above from: UniProt accession
P50219
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- HB 9 antibodyHB9 antibodyHLXB 9 antibody
- HLXB9 antibodyHomeo box HB9 antibodyHomeobox HB9 antibodyHomeobox protein HB9 antibodyHOXHB9 antibodyMNX1 antibodyMNX1_HUMAN antibodyMotor neuron and pancreas homeobox protein 1 antibodySacral agenesis autosomal dominant (Currarino triad) antibodySCRA 1 antibodySCRA1 antibody
see all
Anti-HB9/HLXB9 antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HB9/HLXB9 antibody (ab92606)Immunohistochemistry analysis of HB9/HLXB9 expression in formalin-fixed, paraffin-embedded Mouse pancreas tissue using: an isotype control (1) or ab92606 at 5µg/ml (2 and 3). -
Western blot - HB9/HLXB9 antibody (ab92606)All lanes : Anti-HB9/HLXB9 antibody (ab92606) at 0.5 µg/ml
Lane 1 : MOLT 4 cell lysate
Lane 2 : MOLT 4 cell lysate with immunizing peptide
Secondary
HRP-conjugated Goat anti-Rabbit IgG
Predicted band size : 41 kDa
References for Anti-HB9/HLXB9 antibody (ab92606)
This product has been referenced in:
- Serre A et al. Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev 21:539-53 (2012). Human . Read more (PubMed: 21561385) »
