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beta 2 Defensin protein (Active) (ab9872)

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Overview

  • Product namebeta 2 Defensin protein (Active)See all beta 2 Defensin proteins and peptides ...
  • Expression hostE. coli

    • Properties

  • Purification notesSterile filtered Greater than 95% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Concentration information loading...
  • Additional notesThe biological activity of this product is determined by its ability to chemoattract immature human dendritic cells using a concentration range of 10.0-100.0 ng/ml.
  • Sequence notesRecombinant Human BD-2 is a 4.3 kDa protein containing 41 amino acid residues: GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab9872 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab9871.

    • Protein info

    • Alternative names
        BD 2BD-2BD2
        beta 2Beta defensin 2Beta-defensin 2Beta-defensin 4ADEF B2DEF B4DEFB 102DEFB 2DEFB 4DEFB102DEFB2DEFB4DEFB4BDefensinDefensin beta 2Defensin beta 4DFB4A_HUMANHBD 2hBD-2HBD2SAP 1SAP1Skin antimicrobial peptide 1Skin-antimicrobial peptide 1
      see all
  • FunctionHas antibacterial activity.
  • Tissue specificityExpressed in the skin and respiratory tract.
  • Sequence similaritiesBelongs to the beta-defensin family. LAP/TAP subfamily.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession O15263 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for beta 2 Defensin protein (Active) (ab9872)

    ab9872 has not yet been referenced specifically in any publications.

    Publishing research using ab9872 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab9872 Submit a Question for ab9872

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    Dear technical team,

    Our customer is looking for beta defensin 2 protein (human, full length) and I have searched ab9872.
    Please check thisis full length protein or not.


    Best regards,

    Thank you for your enquiry.

    The datasheet for ab9872 states the following, and I can confirm this is regrettably not a full length protein (full length protein is over64 amino acids):

    Recombinant Human BD-2 is a 4.3 kDa protein conta...

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    Customer has performed the Dot-Blotprotocolas suggested;please findthe results attached.

    Regarding the storage:
    - antibodies were stored at -20°C.
    - recombinant proteins were reconstituted with 100 ul PBS + 15% glycerol, aliq...

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    Thank you for sending along the dot blots and additional information. We really appreciate the extra troubleshootingeffort.

    Here are my thoughts:

    1. In general it looks like the antibodies are able to detect Defensin in the chorioamnio...

    Read More

    For the technical support,   Please, customer is having problems using human beta defensin antibodies and their respective recombinant proteins in WB applications.   Find bellow the technical questionnaire filled out by the customer.   As the beta def...

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    Thank you for contacting Abcam Technical Team and for taking the time to provide some useful details of the experiments. I am very sorry to hear that your customer is are having problems with 8 of our products.  Special thanks for collecting the troubled ...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"