Overview

  • Product nameAnti-ABCA2 antibody
    See all ABCA2 primary antibodies
  • Description
    Rabbit polyclonal to ABCA2
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 125 and 175 of Human ABCA2 (NP_001597.2).

  • Positive control
    • 293T whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
  • Application notesIP: Use at 5-15 µg/mg of lysate.
    WB: 1/2000 - 1/10000. Predicted molecular weight: 270 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProbable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
    • Tissue specificityHighy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
    • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCA family.
      Contains 2 ABC transporter domains.
    • Cellular localizationEndosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.
    • Information by UniProt
    • Database links
    • Alternative names
      • ABC2 antibody
      • Abca2 antibody
      • ABCA2_HUMAN antibody
      • ATP binding cassette 2 antibody
      • ATP binding cassette sub family A member 2 antibody
      • ATP binding cassette transporter 2 antibody
      • ATP binding cassette, sub family A (ABC1), member 2 antibody
      • ATP binding cassette, sub family A, member 2 antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 2 antibody
      • ATP-binding cassette 2 antibody
      • ATP-binding cassette sub-family A member 2 antibody
      • ATP-binding cassette transporter 2 antibody
      see all

    Anti-ABCA2 antibody images

    • All lanes : Anti-ABCA2 antibody (ab91571) at 0.4 µg/ml

      Lane 1 : 293T whole cell lysate at 50 µg
      Lane 2 : 293T whole cell lysate at 15 µg
      Lane 3 : 293T whole cell lysate at 5 µg

      Developed using the ECL technique

      Predicted band size : 270 kDa


      Exposure time : 3 minutes
    • Detection of ABCA2 by Western Blot of Immunoprecipitate.
      ab91571, at 1 µg/ml, staining ABCA2 in 293T whole cell lysate immunoprecipitated using ab91571 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 3 minutes.

    References for Anti-ABCA2 antibody (ab91571)

    This product has been referenced in:
    • Alla V  et al. E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. Cell Cycle 11:3067-78 (2012). Read more (PubMed: 22871739) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab91571.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"