Overview

  • Product name
  • Description
    Rabbit polyclonal to ABCA5
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to C terminal amino acids 1464-1642 of Human ABCA5 (NM_018672).

  • Positive control
    • Human fetal testis lysate, Human fetal kidney tissue

Properties

  • Form
    Lyophilised:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab99953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24831815
WB 1/500 - 1/1000. Predicted molecular weight: 187 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    May play a role in the processing of autolysosomes.
  • Tissue specificity
    Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCA family.
    Contains 2 ABC transporter domains.
  • Developmental stage
    Expressed in fetal liver, kidney and brain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Lysosome membrane. Late endosome membrane. Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC13 antibody
    • ABCA5 antibody
    • ABCA5_HUMAN antibody
    • ATP binding cassette sub family A (ABC1) member 5 antibody
    • ATP binding cassette A5 antibody
    • ATP binding cassette sub family A member 5 antibody
    • ATP-binding cassette sub-family A member 5 antibody
    • DKFZp451F117 antibody
    • DKFZp779N2435 antibody
    • EST90625 antibody
    • FLJ16381 antibody
    • KIAA1888 antibody
    see all

Images

  • Anti-ABCA5 antibody (ab99953) at 1/500 dilution + Human fetal testis lysate

    Predicted band size : 187 kDa
  • ab99953 at 1/100 dilution, staining ABCA5 in human fetal kidney tissue.

References

This product has been referenced in:
  • DeStefano GM  et al. Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth. PLoS Genet 10:e1004333 (2014). WB, IHC-P, ICC/IF ; Human . Read more (PubMed: 24831815) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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